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nifedipine will improve the stage or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.apalutamide will decrease the extent or effect of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP2C19 inducer, with med